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Chest X-Rays in the ER Predict COVID-19 Severity


May 15, 2020 -- Chest x-rays acquired when patients present in the emergency room (ER) with COVID-19 symptoms can predict the severity of the disease, particularly in young and middle-aged adults, according to a study published May 14 in Radiology.

The study findings demonstrate x-ray's value in helping physicians identify, triage, and treat high-risk patients, wrote a team led by Dr. Danielle Toussie of Mount Sinai Hospital in New York City.

"We demonstrate how valuable x-rays can be during this pandemic because, by evaluating disease in different portions of the lungs, we can predict outcomes, which can potentially help appropriately allocate resources and expedite treatment in the most severe cases," Toussie said in a statement released by the hospital.

The researchers developed an x-ray scoring system to evaluate COVID-19 disease severity in order to better determine which patients need to be hospitalized and/or intubated.

"We came up with the scoring system because we had clinicians asking us what we see on chest x-rays of COVID-19 patients," Toussie said. "We would tell them, 'We see this opacity here or that opacity there,' but then they would ask, 'What does that mean for my patient?' "

Toussie and colleagues evaluated records from 338 COVID-19 patients who were treated at three Mount Sinai locations in March. All underwent chest x-ray in the emergency room; of the total, 145 (43%) were admitted.

The team reviewed race and information on preexisting conditions on each patient, analyzed the x-rays for COVID-19 patterns, and divided them into six zones: upper right, upper left, middle right, middle left, lower right, and lower left. They then developed a scoring system from 0 to 6 to measure disease severity (lower severity scores, 0 to 2; higher scores, 3 to 6). Higher severity scores corresponded with lung involvement in multiple areas.

Overall, the researchers found the following:

  • Patients with the highest scores were 6.2 times more likely to be hospitalized and 4.7 times more likely to be intubated.

  • Men were more likely than women to have higher scores and be admitted to the hospital, but they were not more likely to be intubated.

  • Obese patients were more likely to have higher scores and require hospital admission.

  • The researchers found no significant differences in outcomes between patients of different races or ethnicity when they adjusted for age, gender, comorbidities, and weight.